[HTML][HTML] The testis-specific LINC component SUN3 is essential for sperm head shaping during mouse spermiogenesis
Q Gao, R Khan, C Yu, M Alsheimer, X Jiang… - Journal of Biological …, 2020 - ASBMB
Sperm head shaping is a key event in spermiogenesis and is tightly controlled via the
acrosome–manchette network. Linker of nucleoskeleton and cytoskeleton (LINC) complexes
consist of Sad1 and UNC84 domain–containing (SUN) and Klarsicht/ANC-1/Syne-1
homology (KASH) domain proteins and form conserved nuclear envelope bridges
implicated in transducing mechanical forces from the manchette to sculpt sperm nuclei into a
hook-like shape. However, the role of LINC complexes in sperm head shaping is still poorly …
acrosome–manchette network. Linker of nucleoskeleton and cytoskeleton (LINC) complexes
consist of Sad1 and UNC84 domain–containing (SUN) and Klarsicht/ANC-1/Syne-1
homology (KASH) domain proteins and form conserved nuclear envelope bridges
implicated in transducing mechanical forces from the manchette to sculpt sperm nuclei into a
hook-like shape. However, the role of LINC complexes in sperm head shaping is still poorly …
