[PDF][PDF] Anti-SARS-CoV-2 hyperimmune globulin demonstrates potent neutralization and antibody-dependent cellular cytotoxicity and phagocytosis through N and S …
JM Díez, C Romero, M Cruz, P Vandeberg… - J Infect Dis, 2021 - researchgate.net
Anti-SARS-CoV-2 hyperimmune globulin potently neutralized viral isolates and S-protein
expressing pseudoviruses representing wild type virus and viral variants. This hyperimmune
globulin also induced antibody-dependent cellular toxicity and phagocytosis via antibodies
to the N and S proteins.
expressing pseudoviruses representing wild type virus and viral variants. This hyperimmune
globulin also induced antibody-dependent cellular toxicity and phagocytosis via antibodies
to the N and S proteins.
Anti-severe acute respiratory syndrome coronavirus 2 hyperimmune immunoglobulin demonstrates potent neutralization and antibody-dependent cellular cytotoxicity …
JM Díez, C Romero, M Cruz… - The Journal of …, 2022 - academic.oup.com
Background Although coronavirus disease 2019 (COVID-19) vaccinations have provided a
significant reduction in infections, effective COVID-19 treatments remain an urgent need.
Methods Functional characterization of anti-severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) hyperimmune immunoglobulin (hIG) from human convalescent plasma was
performed by different virus neutralization methodologies (plaque reduction, virus-induced
cytotoxicity, median tissue culture infectious dose [TCID50] reduction, and …
significant reduction in infections, effective COVID-19 treatments remain an urgent need.
Methods Functional characterization of anti-severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) hyperimmune immunoglobulin (hIG) from human convalescent plasma was
performed by different virus neutralization methodologies (plaque reduction, virus-induced
cytotoxicity, median tissue culture infectious dose [TCID50] reduction, and …
