Coronary heart disease (CHD) due to atherosclerosis is the leading cause of death in the
USA, and accelerated CHD has emerged as a leading cause of morbidity and mortality in
diabetic patients in the USA and worldwide. This has highlighted the importance and
urgency of studying the mechanism of diabetic atherosclerosis and exploring therapeutic
options. Due to its unique advantages over other animal models, the mouse is the most used
model for studying the mechanism of diabetes-accelerated atherosclerosis and exploring …